Polarographic Reduction of Hydroxamic Acids.
نویسندگان
چکیده
منابع مشابه
Theoretical Studies on Hydroxamic Acids
Hydroxamic acids find many applications in chemistry and biology and have been the subject of many experimental investigations. Theoretical studies are not as frequent. However, the smallest homolog, formohydroxamic acid (FHA), has been studied at various levels, including high-level ab initio and density functional with large basis sets. All studies indicate that it exists as the Z-amide tauto...
متن کاملPOLAROGRAPHIC AND POTENTIOSTATIC REDUCTION OF CARBODIIMIDES: A MECHANISTIC STUDY
The polarographic reduction of aromatic carbodiimides in anhydrous aprotic solvents goes through a carbene intermediate by a diffusion controlled process in two one-electron steps. The first step is the rate-determining step and converts the carbodiirnide to a radical anion (6) that reduces further by a fast one-electron step to a carbene dianion intermediate (7). This abstracts an oxygen, ...
متن کاملPolarographic Reduction of Benzoate in Acet,pnitrile
The polarographic wave observed for acetonitrile solutions of benzoic acid is due to reduction of the acid proton: the apparent diffusion current constant for the wave increases with concentration of benzoic acid as expected for the reduction of the acidic proton of a slightly dissociated acid. No wave was observed for ethyl benzoate. The situation in respect to the electrochemical reduction of...
متن کاملAntioxidant activity of NSAID hydroxamic acids.
In the present study, seven hydroxamic acid derivatives of nonsteroidal anti-inflammatory drugs (NSAIDs) (ibuprofen, fenoprofen, ketoprofen, indomethacin and diclofenac) were found to possess significant antioxidant, radical scavenging and metal chelating activities. The most active antioxidant and radical scavenger was N-methylhydroxamic acid of diclofenac (ANT = 88.0% and EC50 = 60.1 microg m...
متن کاملChemistry and Biology of Hydroxamic Acids
The action of salicylhydroxamic acid and its halogen derivatives against tuberculosis, fungi, trypanosomae, and the biosynthesis of cholesterol are described. Their hypoglycemic and phospholipid lowering actions are also mentioned. The author suggested, in 1948, the use of salicylhydroxamic acid I (X = Y = Z = R = H)—called SH—as an antitubercular agent [26]. The suggestion was based on the hyp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1957
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.11-1530